Kristine Biller Mattson's professional career continues to climb with an acclaimed performance of The Lord Nelson Mass in Philadelphia with orchestra members from the Philadelphia Orchestra and Curtis Institute. Upcoming, she will be the featured soprano soloist in Górecki's powerful Symphony No. 3 with the North Penn Symphony. Last spring she performed The Bells with the Helena Symphony, The Armed Man: A Mass for Peace with the Rockham Symphony in Detroit and the Mahler 2nd with the North Penn Symphony. In 2008, she was casted in the acclaimed, Margaret Garner as Caroline with Michigan Opera Theater and toured the production in Chicago as well. She shared the stage with renowned mezzo-soprano Denyce Graves who sang the title role. The Chicago Sun acclaimed: "Kristine Biller Mattson is a lovely soprano and one to look for in the future." The Windy City stated: "Ms. Mattson's voice possessed smoky depths with bell-like highs while maintaining a spine of steel on stage." This year, she has already performed Adina in L'Elisir d'Amore, and has sung the soprano soloist in the Beethoven's C Major Mass and the Verdi Requiem.

In the spring of 2008, Kristine was selected to perform a concert in honor of Ms. Ruth Ann Swenson. In the winter 2007, Kristine performed Micaela with the Helena Symphony. She returned to Philadelphia and was chosen to sing for The Voice Foundation, honoring amongst others, Mr. Robert Goulet and Ms. Harolyn Blackwell. In the fall 2007, Kristine sang with the Opera Company of Philadelphia in Hansel and Gretel as the Sandmännchen. This is her fourth role with the Opera Company of Philadelphia. Her other roles include Frasquita in Carmen, soprano lead, Wanda in the Grand Duchess of Gerolstein and Caroline in the world premiere-tour of Margaret Garner. Because of these opportunities, Kristine has shared the stage with singers like Stephanie Blythe, Denyce Graves, and Angela Brown, to name a few. In 2006, she sang Clorinda in La Cenerentola with Michigan Opera Theater opposite another well-known mezzo, Ms. Vivica Genaux. In the fall, 2005 she sang another world premiere piece, The Happy Prince, with Kentucky Opera.

Kristine placed 2nd in the Florida Grand Competition in 2004. She graduated from Indiana University in May, 2002. While attending Indiana with a full scholarship, she was selected to perform five leading roles. She began performing within two months of being there in Carmen as Micaela, followed by Mimi in La Bohème, Princess Ninetta in Love for Three Oranges, Adina in L'Elisir d'Amore and Manon in Manon. She also won the Palm Beach Opera Competition twice: placing 2nd and 4th. While still in undergraduate school she began her professional career with Opera Roanoke singing Second Lady in Die Zauberflöte. She went on to sing with them several times thereafter.